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Future Trends in Precision Medicine

Future Trends in Precision Medicine

SGRH 30 Oct 2024

As we advance into the future, the convergence of artificial intelligence, genomics, and big data analytics is driving unprecedented progress in personalized healthcare solutions. Emerging trends suggest a shift from the traditional "one-size-fits-all" approach to highly targeted therapies that consider a patient's unique molecular profile. This shift promises more effective treatments, reduced adverse effects, and improved patient outcomes while potentially lowering healthcare costs through more efficient and targeted interventions.

Personalized treatment is already altering some illnesses management and is anticipated to be a key trend in medicine progression in the future decades. Some of the key future trends that are expected to shape the growth and evolution of precision medicine are:

Expanded Use of Genomics: The guiding ideology behind precision medicine has put genomic sequencing and analysis in high regard. Costs associated with sequencing continue to come down, and it will be more feasible to sequence the whole genome with immense ease. This will make it possible to use genomics in even more patients to improve doctors’ understanding of the risks and to optimize the treatment plan based on genes. Affordability in genomics and extension of the genomics engine could lead to enhanced disease risk analysis, early disease prevention, and optimized treatment results.

Growth of Biobanks : More comprehensive, well-characterized specimens with genetic material and proteins in centralized repositories, mainly blood, and tissue, will be essential for further complex assessment of the human genome in the attempt to deliver individualized treatment. Creating large biobanks in different populations to cover a wide diversity will help to identify genetic factors that play for drug response and disease risk. Biobanks that are non-profit and commercial are already increasing in number worldwide and are expected to increase greatly as genomics is integrated with precision medicine.

More Turn to Integrative Analysis :The focus is on analyzing traditional SNPs (Single Nucleotide Polymorphism) and QTLs (Quantitative Trait Locus) systematically and in isolation to consider the complex system of genetics and biomarker interactions. For instance, incorporating proteins, metabolites, microbiomes, and genomics for instance in a non-hypothetical sense could mean that diagnosis, as well as prognosis, will be more accurate as will the choice of treatments for such patients. The high dimensionality of such sources and a potentially large number of inputs mean that machine learning methods will have an important role to play in pattern recognition.

The results also imply paying more attention to lifestyle factors: At the moment, personalization is mainly associated with genomics or genetic variation in the context of precision medicine. However, there is growing evidence that factors such as diet, exercise, sleep, and stress levels contribute considerably to the development of the disease. For instance, exercise, dietary changes, and other non-pharmacological interventions can be used as first-line interventions before the use of medications. Further attempts shall be made to integrate genomic profiling with lifestyle biomonitoring to detect vulnerable individuals and prevent and control lifestyle-associated conditions such as diabetes and hypertension among others, as suggested by the specialists from the best medicine hospital in Delhi.

Concentration on information that helps in taking action : Currently, one of the main issues of Precision Medicine is a timely interpretation of permutations of genomics, clinical notes, and patient lifestyles for the decision-making process on the next manageable steps forward. Coordinated attempts to demonstrate the clinical utility of the new biomarkers and make recommendations based on precision diagnostics are suggested. Anyone claiming such potential could also be exposed to higher levels of regulation that could affect genomic prediction.

Health Information Exchange: The realization of precision medicine aims will therefore require improvement in the interoperability of data with different institutions and technologies. The essential investment will be directed at creating an efficient framework for exchanging the patient’s data unhindered by strict protocols governing the transfer of the data’s ownership. There are several Government-associated initiatives to enhance Health Information Exchanges that tend to increase in the future years too.

Precision Medicine is emerging at its pace and slow and steady progress is seen on many fronts such as; genomics, big data, biobanks, lifestyle monitoring, health information infrastructure, reimbursement, and policy. In the coming decades, precision medicine will lead to growth and adoption. Improved levels of diagnosis accompanied by increasing focus on the patients as individuals can bring savings and other important health effects to the healthcare system. Analytic precision medicine strategies will most definitely revolutionize virtually all sectors of medicine shortly. To know more, book an appointment at Sir Ganga Ram Hospital today.