Md pediatric, Intensivist, Pulmonology and allergy
1) IAP Guideline on Practicing Safely During COVID-19 Era: Clinics and Small Establishments.
Basavaraja GV, Chandrasekar S, Bansal A, Gupta D, Parekh BJ, Kamath SS, Desai S, Nagar P, Shah N, Bhadra A, Chitkara AJ; For Indian Academy of Pediatrics.Indian Pediatr. 2021 Apr 15;58(4):383-390. doi: 10.1007/s13312-021-2201-y.PMID: 33883314
2) Novel Coronavirus 2019 (2019-nCoV) Infection: Part I - Preparedness and Management in the Pediatric Intensive Care Unit in Resource-limited Settings.
Ravikumar N, Nallasamy K, Bansal A, Angurana SK, Basavaraja GV, Sundaram M, Lodha R, Gupta D, Jayashree M; Intensive Care Chapter of Indian Academy of Pediatrics.Indian Pediatr. 2020 Apr 15;57(4):324-334. doi: 10.1007/s13312-020-1785-y. Epub 2020 Mar 29.PMID: 32238612
3) 2) Novel Coronavirus 2019 (2019-nCoV) Infection: Part II - Respiratory Support in the Pediatric Intensive Care Unit in Resource-limited Settings. Sundaram M, Ravikumar N, Bansal A, Nallasamy K, Basavaraja GV, Lodha R, Gupta D, Odena MP, Ashwath RNR, Jayashree M; Intensive Care Chapter of Indian Academy of Pediatrics.Indian Pediatr. 2020 Apr 15;57(4):335-342. doi: 10.1007/s13312-020-1786-x. Epub 2020 Mar 29.PMID: 32238613
4) A CLINICAL CASE DEFINITION FOR POST COVID-19 CONDITION IN CHILDREN AND ADOLESCENTS BY EXPERT CONSENSUS 16 February 2023. WHO-2019-nCoV-Post-COVID-19-condition-CA-Clinical-case-definition-2023.1-eng (1).pdf . WHO/2019-nCoV/Post_COVID-19_condition/CA/Clinical_case_definition/2023.1
Publication
1. Sachdev A, Gupta N, Singh BP, D Choudhari N, Sharma N, Gupta S, Gupta D, Chugh P. Indication Based Timing of Tracheostomy and its Effects on Outcome in the Pediatric Intensive Care Unit. Pediatr Pulmonol. 2022 May 4. doi: 10.1002/ppul.25952. Epub ahead of print. PMID: 35506424.
2. Gupta D , Dhingra S . Electrocardiometry Fluid Responsiveness in Pediatric Septic Shock. Indian J Crit Care Med. 2021 Feb;25(2):123-12 doi: 10.5005/jp-journals-10071-23745.
3. Wadhwani M, Jajoo M, Sakia D, Gupta D . Ocular Presentation in Multiple Inflammatory Syndrome in Children. J Pediatr Ophthalmol Strabismus . 2022 Jan-Feb;59(1):65-66.doi: 10.3928/01913913-20211130-01. Epub 2022 Jan 1.
4. Chhawchharia R, Gupta N, Gupta D, Agarwal P. Plastic Bronchitis: A Manifestation of Dander Hypersensitivity. Indian Pediatr. 2020 Aug 15;57(8):760-761.PMID: 32844770
5. Mehra B, Aggarwal V, Kumar P, Gupta D, Kundal M, Kumar A, Dugaya SK.
MIS-C is a Clinically Different Entity from Acute COVID-19 in Adults. Indian J Crit Care Med. 2021 Aug;25(8):954-955. doi: 10.5005/jp-journals-10071-23927.PMID: 34733044
6. Mehra B, Pandey M, Gupta D, Oberoi T, Jerath N, Sharma R, Lal N, Singha C, Malhotra B, Manocha V, Simalti AK, Arya Y, Dugaya SK, Kalra S, Chitkara AJ, Sachdev A, Gupta N. COVID-19-associated Multisystem Inflammatory Syndrome in Children: A Multicentric Retrospective Cohort Study. Indian J Crit Care Med. 2021 Oct;25(10):1176-1182. doi: 10.5005/jp-journals-10071-23996. PMID: 34916752; PMCID: PMC8645810.
7. Sachdev A, Pandharikar N, Gupta D, Gupta N, Gupta S, Venkatraman ST. Hospital-acquired Hyponatremia in Pediatric Intensive Care Unit. Hospital-acquired Hyponatremia in Pediatric Intensive Care Unit.Indian J Crit Care Med. 2017 Sep;21(9):599-603. doi: 10.4103/ijccm.IJCCM_131_17.PMID: 28970661
8. Sachdev A, Pathak D, Gupta N, Simalti A, Gupta D, Gupta S, Chugh P. Early Predictors of Mortality in Children with Severe Dengue Fever: A Prospective Study. Pediatr Infect Dis J. 2021 Sep 1;40(9):797-801. doi: 10.1097/INF.0000000000003179. PMID: 34321449.
9. Sachdev A, Khatri A, Saxena KK, Gupta D, Gupta N, Menon GR. Chest sonography versus chest radiograph in children admitted to paediatric intensive care - A prospective study. Trop Doct. 2021 Jul;51(3):296-301. doi: 10.1177/00494755211016650. Epub 2021 May 27. PMID: 34041979
10. .Sachdev A, Gupta N, Khatri A, Jha G, Gupta D, Gupta S, Menon GR Flexible Fiberoptic Bronchoscopy in Non-ventilated Children in Pediatric Intensive Care Unit: Utility, Interventions and Safety..Indian J Crit Care Med. 2023 May;27(5):358-365. doi: 10.5005/jp-journals-10071-24449.PMID: 37214112
11. Sachdev A, Chaudhari ND, Singh BP, Sharma N, Gupta D, Gupta N, Gupta S, Chugh P. Tracheostomy in Pediatric Intensive Care Unit-A Two Decades of Experience. Indian J Crit Care Med. 2021 Jul;25(7):803-811. doi: 10.5005/jp-journals-10071-23893. PMID: 34316177; PMCID: PMC8286380.
12. Gupta N, Sachdev A, Gupta D, Gupta S. Assessment of airway reversibility in asthmatic children using forced oscillation technique - A single-center experience from North India. Lung India. 2021 May-Jun;38(3):229-235. doi: 10.4103/lungindia.lungindia_354_20. PMID: 33942746; PMCID: PMC8194442.
13. Gupta N, Sachdev A, Gupta S, Gupta D. COVID-19-A Sputnik Moment to Revitalize Oscillometry. Indian J Pediatr. 2021 Jun;88(6):613. doi: 10.1007/s12098-021-03709-5. Epub 2021 Mar 2. PMID: 33651304; PMCID: PMC7922720.
14. Gupta N, Sachdev A, Gupta S, Gupta D. High-flow oxygen therapy in COVID times: Where affordability meets utility. Pediatr Pulmonol. 2021 Jun;56(6):1782-1783. doi: 10.1002/ppul.25276. Epub 2021 Feb 1. PMID: 33524246; PMCID: PMC8014044.
15. Gupta N, Sachdev A, Gupta D. Oscillometry-A reasonable option to monitor lung functions in the era of COVID-19 pandemic. Pediatr Pulmonol. 2021 Jan;56(1):14-15. doi: 10.1002/ppul.25121. Epub 2020 Oct 26. PMID: 33104290
16. Neeraj Gupta, Anil Sachdev, Dhiren Gupta, Suresh Gupta. Oscillometry -The future of estimating pulmonary functions - Karnataka Pediatric Journal. January 2021DOI: 10.25259/KPJ_25_2020.
17. Mukul Pandey, Anil Sachdev, Neeraj Gupta, Dhiren Gupta. Comparison of Heated Humidified High Flow Nasal Cannula And Non-Invasive Ventilation On Post- Extubation Outcome In High Risk Children - A Randomized Clinical Non-Inferiority Trial. July 2020 DOI: 10.22541/au.159583183.31412744.
18. Neeraj Gupta, Dhiren Gupta, Anil Sachdev. Approach to an Adolescent with suspected Tuberculosis - Indian Journal of Adolescent Medicine (Special Section) July 2020.
19. Anil Sachdev, Nishant Wadhwa, Naimish Mehta, Dhiren Gupta. A study of critical care issues in pediatric liver transplantation. July 2020 Journal Of Pediatric Critical Care 7(4)DOI: 10.4103/JPCC.JPCC_46_20.
14 Dhiren Gupta, Simalti Ak, Neeraj Gupta, Anil Sachdev. Personal protective equipment during COVID-19 epidemic. May 2020 JOURNAL OF PEDIATRIC CRITICAL CARE 7(7):22DOI: 10.4103/JPCC.JPCC_75_20.
12. Krishna Mohan Gulla, Tanushree Sahoo, Dhiren Gupta, Anil Sachdev. Prediction of early intensive care unit mortality with serial serum lactate levels and its clearance in children with septic shock and multiorgan dysfunction syndrome. November 2020 JOURNAL OF PEDIATRIC CRITICAL CARE 7(6):321DOI: 10.4103/JPCC.JPCC_114_20.
13. Neeraj Gupta, Anil Sachdev, Dhiren Gupta, Ritika Chhawchharia. Impulse Oscillometry- A Novel Tool In Pediatric Office For Measuring Lung Function; 1st National Congress on Asthma, Allergy & Immunology (ALLERGOCON), Vellore,DOI:10.13140/RG.2.2.10887.65443, Jan 2019.
14. Pandey M, Gupta D, Gupta N, Sachdev A. Use of Transpulmonary Pressure Monitoring in the Management of Extra pulmonary Pediatric Acute Respiratory Distress Syndrome With multi organ dysfunction syndrome (MODS): Are We Peepophobic? Clin Med Insights Case Rep. 2019 Apr 12;12:1179547619842183. doi: 10.1177/1179547619842183. eCollection 2019.
15. Gulla KM, Gupta D, Sachdev A. Listeria meningitis in an immunocompetent child. Trop Doct. 2019 May 13:49475519847331. doi: 10.1177/0049475519847331. [Epub ahead of print] ndian Pediatr. 2019 Jul 15;56(7):587-593.
16. Sachdev A1 , Chhawchharia R2 , Gupta D2 , Gupta N2 . Flexible Fiberoptic Bronchoscopy Directed Interventions in Neonatal Intensive Care Unit. Indian Pediatr. 2019 Jul 15;56(7):563-565.
17. Rauf A, Gupta D, Sachdev A, Gupta N, Gupta S, Kumar P, Sabharwal R. Neurally Adjusted Ventilatory Assist: An Early Clue to Diagnosis of Congenital Central Hypoventilation Syndrome. Indian J Crit Care Med. 2019 Nov;23(11):536-537. doi: 10.5005/jp-journals10071-23286.
18. Gupta N, Agarwal P, Sachdev A, Gupta D. Allergy Testing - An Overview. Indian Pediatr. 2019 Nov 15;56(11):951-957.
19. Anil Sachdev1 , Neeraj Kumar Sagar2 , Dhiren Gupta2 , Neeraj Gupta2 , Suresh Gupta 2. Efficacy of Adjuvant Colistimethate Sodium Nebulization in Ventilator Associated Pneumonia in Pediatric Intensive Care Unit - A Randomized Controlled Study .Journal of Pediatric Critical Care . Year : 2019 | Volume : 6 | Issue : 3 | Page : 15 - 20 P - ISSN : 2349-6592 | E - ISSN : 2455-7099.
20. Anil Sachdev, Sameer Punia, Neeraj Gupta, Dhiren Gupta ,Suresh Gupta, Non-invasive Positive Pressure Ventilation Immediately after Extubation in Children - A Randomized Study. December 2019 DOI: 10.21304/2019.0606.00539.
21. Gupta N, Sachdev A, Gupta D, Gupta S. Safety profile of blind bronchial sampling-A prospective study in pediatric intensive care unit. Pediatr Pulmonol. 2018 Jul;53(7):942- 947. doi: 10.1002/ppul.23989. Epub 2018 Mar 22. PMID: 29566462.
22. Bhai P, Bijarnia-Mahay S, Puri RD, Saxena R, Gupta D, Kotecha U, Sachdev A, Gupta D, Vyas V, Agarwal D, Jain V, Bansal RK, Kumar TG, Verma IC. Clinical and molecular characterization of Indian patients with fructose-1, 6-bisphosphatase deficiency: Identification of a frequent variant (E281K). Ann Hum Genet. 2018 Sep;82(5):309-317. doi: 10.1111/ahg.12256. Epub 2018 May 18. PMID: 29774539.
23. A Sachdev, S. Punia, Dhiren Gupta, S. Gupta. Post-Extubation Use of Non-Invasive Ventilation In Children- A Randomized Controlled Trial Pediatric Critical Care Medicine 19:239 · June 2018 with 1 Reads DOI: 10.1097/01.pcc.0000538072.44094.31.
24. Sachdev A, Simalti A, Kumar A, Gupta N, Gupta D, Chugh P. Outcome Prediction Value of Red Cell Distribution Width in Critically-ill Children. Indian Pediatr. 2018 May 15;55(5):414-416. PMID: 29845956.
25. Gupta N, Sachdev A, Gupta D, Gupta S, Gupta D, Nanavati J. Autism and Allergy - Are They Linked? Indian J Pediatr. 2018 Dec;85(12):1132-1133. doi: 10.1007/s12098-018- 2743-8. Epub 2018 Jul 18. PMID: 30019312.
26. Neeraj Gupta, Abdul Rauf Kk, Anil Sachdev, Dhiren Gupta. Murine Typhus infection presenting with Multi organ dysfunction in a child; A case report. Current Medicine Research and Practice Journal Article · October 2018 DOI: 10.1016/j.cmrp.2018.09.002.
27. Vohra R, Sachdev A, Gupta D, Gupta N, Gupta S. Refractory Status Asthmaticus: A Case for Unconventional Therapies. Indian J Crit Care Med. 2018 Oct;22(10):749-752. doi: 10.4103/ijccm.IJCCM_191_18. PMID: 30405290; PMCID: PMC6201647.
28. Gupta N, Sachdev A, Gupta D, Radhakrishnan N. Disseminated Cryptococcosis in an Immunocompetent Toddler. Indian Pediatr. 2017 Feb 15;54(2):145-146. doi: 10.1007/s13312-017-1018-1. PMID: 28285287.
29. Sachdev A, Ghimiri A, Gupta N, Gupta D. Pre-decannulation flexible bronchoscopy in tracheostomized children. Pediatr Surg Int. 2017 Nov;33(11):1195-1200. doi: 10.1007/s00383-017-4152-x. Epub 2017 Sep 6. PMID: 28879448.
30. Sachdev A, Pandharikar N, Gupta D, Gupta N, Gupta S, Venkatraman ST. Hospitalacquired Hyponatremia in Pediatric Intensive Care Unit. Indian J Crit Care Med. 2017 Sep;21(9):599-603. doi: 10.4103/ijccm.IJCCM_131_17. PMID: 28970661; PMCID: PMC5613613.
31. Pandharikar N, Sachdev A, Gupta N, Gupta S, Gupta D. Chest trauma: A case for single lung ventilation. Indian J Crit Care Med. 2016 Apr;20(4):248-50. doi: 10.4103/0972- 5229.180050. PMID: 27303142; PMCID: PMC4906333.
32. Sachdev A, Mehra B, Mohanty A, Gupta D, Gupta N. Refractory pediatric cardiogenic shock: A case for mechanical support. Indian J Crit Care Med. 2016 Nov;20(11):680-683. doi: 10.4103/0972-5229.194012. PMID: 27994387; PMCID: PMC5144534.
33. Sachdev A, Anand P, Gupta D. Lipoid pneumonia - an unusual cause of acute respiratory distress syndrome. Indian Pediatr. 2015 Jan;52(1):63-4. doi: 10.1007/s13312-015-0569- 2. PMID: 25638190.
34. Gulla KM, Sachdev A, Gupta D, Gupta N, Anand K, Pruthi PK. Continuous renal replacement therapy in children with severe sepsis and multiorgan dysfunction - A pilot study on timing of initiation. Indian J Crit Care Med. 2015 Oct;19(10):613-7. doi: 10.4103/0972-5229.167044. PMID: 26628828; PMCID: PMC4637963.
35. Anil Sachdev, Sandeep Dhingra. Viscoelastic Hemostatic Assays; Journal of Pediatric Critical Care Vol.2- No. 4 October- December 2015.
36. Yogesh Kumar Arya, Anil Sachdev, Dinesh Kaul. Tuberculosis-A morbidity in childhood pneumonia.Ganga Ram Journal July 2015.
37. D Gupta, A Sachdev. N Gupta. A K Simalti. D. Gupta. Home Ventilation in Children; Journal of Nepal Paediatric Society 35(1): 85. October 2015 with 15 Reads DOI: 10.3126/jnps.v35i1.11887.
38. Gupta Neeraj, Sachdev Anil, Gupta Dhiren. Cardiac Pacing in Pediatric Intensive Care Unit; Practical Approach to Pediatric Intensive Care III Edition 2015 , ISBN 978-93-5152- 739-8.
39. Sachdev A, Gulla K.M, Anand K, Raheja K, Gupta N, Gupta D. Transfluthrin Poisoning Resulting in Intra Vascular Haemolysis and Methemoglobinemia in G6PD DeficiencyTreatment Challenge; J Clin Toxicol; ISSN:2161-0495 JCT, an open access journal ; 2015 Volume 5 • Issue 2 • 1000247.
40. Sachdev A, Chugh K, Raghunathan V, Gupta D, Wattal C, Menon GR. Diagnosis of bacterial ventilator-associated pneumonia in children: reproducibility of blind bronchial sampling. Pediatr Crit Care Med. 2013 Jan; 14(1):e1-7. doi: 10.1097/PCC.0b013e318260129d. PMID: 23269358.
41. A Sachdev, K Chugh, M Sethi, D Gupta, C Wattal and G Menon. Clinical Pulmonary Infection Score to Diagnose Ventilator- associated Pneumonia in children- Indian Pediatrics 2011, 12;949-954.
42. Sachdev A, Chugh K, Krishana A, Gupta D. Congenital tracheobiliary fistula: a case report with review of literature. Pediatr Surg Int. 2011 Aug;27(8):899-905. doi: 10.1007/s00383-011-2879-3. Epub 2011 Apr 24. PMID: 21516501.
43. Sachdev A, Chugh K, Sethi M, Gupta D, Wattal C, Menon G. Diagnosis of ventilatorassociated pneumonia in children in resource-limited setting: A comparative study of bronchoscopic and nonbrochoscopic methods. Pediatr Crit Care Med2010; Mar:11(2)258–66. DOI: 10.1097/PCC.0b013e3181bc5b00
44. Chugh K, Sachdev A, Gupta S, Gupta D (eds). Manual of Pediatric intensive care and emergency medicine 2nd ed. Department of Pediatrics, Sir Ganga Ram Hospital ; 2010:1- 12.
45. Sachdev A, Sharma R, Gupta D. Cerebrovascular complications in pediatric intensive care unit. Indian J Crit Care Med. 2010 Jul;14(3):129-40. doi: 10.4103/0972-5229.74171. PMID: 21253346; PMCID: PMC3021828.
46. Khilnani P, Singhi S, Lodha R, Santhanam I, Sachdev A, Chugh K, Jaishree M, Ranjit S, Ramachandran B, Ali U, Udani S, Uttam R, Deopujari S. Pediatric Sepsis Guidelines: Summary for resource-limited countries. Indian J Crit Care Med. 2010 Jan;14(1):41-52. doi: 10.4103/0972-5229.63029. PMID: 20606908; PMCID: PMC2888329.
47. Garg G, Sachdev A, Gupta D. Pulmonary alveolar proteinosis. Indian Pediatr. 2009 Jun;46(6):521-3. PMID: 19556662.
48. Agrawal S, Sachdev A, Gupta D, Chugh K. Platelet counts and outcome in the pediatric intensive care unit. Indian J Crit Care Med. 2008 Jul;12(3):102-8. doi: 10.4103/0972- 5229.43678. PMID: 19742257; PMCID: PMC2738316.
49. Sachdev A, Seth S. Necrotizing fascitis. Indian Pediatr. 2004 Jun;41(6):623. PMID: 15235174.
50. Sachdev A, Gupta DK, Soni A, Chugh K. Central venous catheter colonization and related bacteremia in pediatric intensive care unit. Indian Pediatr. 2002 Aug;39(8):752-60. PMID: 1219668
51. COVID-19 associated Multisystem Inflammatory Syndrome inChildren: A Multicentric Retrospective Cohort StudyBharat Mehra1 , Mukul Pandey2 , Dhiren Gupta3 , Tania Oberoi4 , Nameet Jerath5 , Rachna Sharma6 , NareshLal7 , Chandrasekhar Singha8 , Bhavana Malhotra9 , Vinamra Manocha10 , Ashish K Simalti11 , Yogesh Arya12 ,Sandeep K Dugaya13 , Swati Kalra14 , Amar J Chitkara15 , Anil Sachdev16 , Neeraj Gupta1
(16) (PDF) COVID-19 associated Multisystem Inflammatory Syndrome in Children: A Multicentric Retrospective Cohort Study. Available from: https://www.researchgate.net/publication/354967528_COVID-19_associated_Multisystem_Inflammatory_Syndrome_in_Children_A_Multicentric_Retrospective_Cohort_Study#fullTextFileContent [accessed Jun 11 2023].
52. Sachdev A, Sharma R, Gupta D .Cerebrovascular complications in pediatric intensive care unit..Indian J Crit Care Med. 2010 Jul;14(3):129-40. doi: 10.4103/0972-5229.74171.PMID: 21253346
53. Ramzan R, Ramzan SP, Gupta D, Arora S, Sanjeev A . Pediatric intensive care unit: an essential service to improve survival of childhood cancer in developing world..Indian J Pediatr. 2012 Dec;79(12):1669-70. doi: 10.1007/s12098-012-0686-z.PMID: 22290629
54. Yadav SP, Sachdeva A, Gupta D, Sharma SD, Kharya G .Control of massive bleeding in dengue hemorrhagic fever with severe thrombocytopenia by use of intravenous anti-D globulin..Pediatr Blood Cancer. 2008 Dec;51(6):812-3. doi: 10.1002/pbc.21708.PMID: 18683235
55. Gupta D, Chugh K, Sachdev A, Soni .ICU management of severe malaria. A.Indian J Pediatr. 2001 .Nov;68(11):1057-61. doi: 10.1007/BF02722357.PMID: 11770242
56. Soni A, Chugh K, Sachdev A, Gupta D .Management of dengue fever in ICU..Indian J Pediatr. 2001 Nov;68(11):1051-5. doi: 10.1007/BF02722356.PMID: 11770241
57. D Gupta . Role of lactate in critically ill children. Indian journal of critical care medicine . 2004 , 8 ,173-181
COVID RELATED PUBLICATIONS
1. Corona viruses in Evidence based medicine in management in Pediatric infectious diseases 3rd edition 2022, IAP . Editor: Dhanya dharmopalan
2. COVID-19 associated Multisystem Inflammatory Syndrome in Children: A Multicentric Retrospective Cohort Study; Indian Journal of Critical Care Medicine, Volume 25 Issue 10 (October 2021) 2.
3. High-flow oxygen therapy in COVID times: Where affordability meets utility; Pediatric Pulmonology. 2021;56:1782- https://doi.org/10.1002/ppul.252763.
4. Management Principles of COVID-19 in Adolescents and Children - Indian Journal of Adolescent Medicine (Special Section); Indian J Adolescent Medicine, Volume 2- June 2020
5. Novel Coronavirus 2019 (2019-CoV) Infection: Part I - Respiratory Support in the Pediatric Intensive Care Unit in Resource-limited Settings; Indian Pediatrics 342 Volume 57_April 15, 2020
6. Oscillometry - A reasonable option to monitor lung functions in the era of COVID-19 pandemic; Pediatric Pulmonology.2021;56:14-15.
7. COVID-19-A Sputnik Moment to Revitalize Oscillometry; The Indian Journal of Pediatrics (June 2021) 88(6):613, https://doi.org/10.1007/s12098-021-03709-57.
8. Pediatric intensive care management in coronavirus infection-19; JOURNAL OF PEDIATRIC CRITICAL CARE January 2020, DOl: 10.4103/1PCCJPcc 77 20.8.
9. Personal protective equipment during COVID-19 epidemic; Journal of Pediatric Critical Care | Volume 7 Supplement 1| May 2020
10. Corona viruses Dhiren Gupta. A K Simalti. Pediatric Intensive Care Unit Protocols. IJPP Series 13 March 2022 11. Long covid in Adolescents (being written ) for adolescent medicine
11. IP Guideline on Practicing Safely During COVID-19 Era: Clinics and Small Establishments; Indian Pediatrics Volume 58 April 15, 2021, 383-390
12. Use Of Personal Protective Equipments During Covid-19 Pandemic In Resource Limited Settings - The Barest Minimum Needed; Indian Journal Of Practical Pediatrics 2020;22(2): 140-14