Dr. Evanka Madan is a distinguished Consultant and Assistant Professor at Sir Ganga Ram Hospital, New Delhi, India. She holds a Doctor of Philosophy (Ph.D.) in Cancer Biochemistry from AIIMS, New Delhi, and an M.Sc. from PGIMER, Chandigarh.
Dr. Madan has nine years of postdoctoral research experience at prestigious institutions such as IGIB, NII, and JNU. With a robust background in Cancer Biology, Cardiometabolic Disorders, and Host-Pathogen Interactions, she has earned significant acclaim in her field. During her postdoctoral tenure, she guided and assisted numerous Ph.D. and M.Sc. students with their research projects and actively taught Molecular Medicine classes.
Her research focuses on drug discovery for parasitic diseases, particularly Leishmania. Dr. Madan has been recognized with numerous awards, including the Scientist Pool Officer by CSIR and the Best Young Researcher Award at the Science Conclave cum NBRCOM.
She has also made substantial contributions through international collaborations, including research stints at Albert Einstein College of Medicine, New York. Dr. Madan's work has been featured in prominent journals, and she has filed a patent, reflecting her commitment to advancing biomedical research and therapy. Additionally, she has received numerous awards for her oral and poster presentations at national and international conferences in the United States, Europe, Australia, UAE, and India.
Publications
Evanka Madan, Bhawana Dikshit, Srinivasan Gowda, Chitrangda Srivastava, Chitra Sarkar, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol. “FAT1 is a novel upstream regulator of HIF1α and invasion of high grade glioma”. Published in International Journal of Cancer; August, 2016; 139, 2570–2582
Bhawana Dikshit, Khushboo Irshad, Evanka Madan, Nupur Aggarwal, Chitra Sarkar, P Sarat Chandra, Deepak K Gupta, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol. “FAT1actsasanupstreamregulatorofoncogenicandinflammatorypathways,viaPDCD4,ingliomacells”. Published in Oncogene; January, 2013; 32, 3798–3808
Evanka Madan, Madhu Puri, Rohini Muthuswami, Dan Zilberstein, Rentala Madhubala. “Leishmania parasite arginine deprivation response pathway influences the host macrophage lysosomal arginine sensing machinery” Published on BioRxiv; September, 2021
Ifeoma Ezenyi#, Evanka Madan#, Jhalak Singhal, Ravi Jain, Amrita Chakrabarti, Gajala Deethamvali Ghousepeer, Ramendra Pati Pandey, Ngozichukwuka Igoli, John Igoli, Shailja Singh. “Screening of traditional medicinal plant extracts and compound identifies a potent antileishmanial diarylheptanoid from Siphonochilus aethiopicus”. Published on SSRN (-id4136064); June 2022 & Published in Journal of Biomolecular Structure and Dynamics; April 2023, #Contributted equally
Pallavi Srivastava#, Ruby Bansal1#, Evanka Madan, Rumaisha Shoaib, Jhalak Singhal, Amandeep Kaur Khlon, Aashima Gupta, Swati Garg, Prince Upadhyay, Soumya Pati, Anand Ranganathan, Shailja Singh. “Identification of de novo peptide against palmitoyl acyltransferase 6 to block survivability and infectivity of Leishmania donovani aethiopicus”. Accepted for publication in ACS Infectious Diseases; April 2024, #Contributted equally
Shital, Evanka Madan, Angamuthu Selvapandiyan and Nirmal K. Ganguly". “An update on recombinant vaccines against leishmaniasis". Submitted to IJMR (IJMR_1040_2024), July, 2024
Ankita Behl#, Rumaisha Shoaib#, Fernando De Leon, Geeta Kumari#, Monika Saini#, Evanka Madan#, Vikash Kumar, Harshita Singh, Jyoti Kumari, Preeti Maurya, Swati Garg, Prakash Chandra Mishra, Christoph Arenz, Shailja Singh. “Human malaria parasite cold shock protein plays an essential role in asexual and sexual stage development and presents a druggable target”. Published in iScience; February 2023. #Contributted equally
Harsimran Brar and Gargi Roy, Akanksha Kanojia, Evanka Madan, Rentala Madhubala, Rohini Muthuswami. “Chromatin-remodelling factor BRG1 is a negative modulator of L. donovani in IFNY stimulated and infected THP-1 cells” Published in Journal of Frontiers in Cellular and Infection Microbiology; April, 2022
Sashi Bhusan Ojha, Raj Kumar Sah, Evanka Madan, Ruby Bansal, Shaktirekha Roy, Shailja Singh. “Methanol extract of Cuscuta reflexa Roxb. possess anti-malarial activity in vitro and in vivo”. Published in Current Microbiology Journal; April, 2022
Madhu Puri, Har Simran Kaur Brar, Evanka Madan, Rajesh Srinivasan, Kapil Rawat, Sai Siva Gorthi, GEETA KUMARI, Raj Kumar Sah, Sashi Bhusan Ojha, Subhendu Panigrahi, Gunanidhi Dhangadamajh, Rohini Muthuswami, Shailja Singh and Rentala Madhubala. “Rapid diagnosis of Plasmodium falciparum malaria using a point-ofcare loop-mediated isothermal amplification device”. Published in Journal of Frontiers in Cellular and Infection Microbiology; August 2022
Madhu Puri, Harsimran Brar, Nimisha Mittal, Evanka Madan, Rajesh Srinivasan, Kapil Rawat, Srija Moulik, Mitali Chatterjee, Sai Siva Gorthi, Rohini Muthuswami and Rentala Madhubala. “Rapid diagnosis of Leishmania infection with a portable loop-mediated isothermal amplification device”. Published in Journal of Biosciences; August, 2021
Raj Sah, Sakshi Anand, Waseem Dar, Ravi Jain, Geeta Kumari, Evanka Madan, Monika Saini, Aashima Gupta, Nishant Joshi, Rahul Hada, Nutan Gupta, Soumya Pati, and Shailja Singh. “Host-Erythrocytic Sphingosine-1-phosphate regulates Plasmodium histone deacetylase activity and exhibits epigenetic control over cell death and differentiation”. Published in Spectrum Journal; January 2023
Swati Garg#, Pragya Gupta#, Akshay Munjal# *, Geeta Kumari# *, Shreeja Biswas# *, Evanka Madan, Monika Saini, Ankita Behl, Akriti Srivastava, Ravi Jain, Amandeep Kaur, Preeti Maurya, Jhalak Singhal, Abir Mandal, R Ayana, Soumya Pati, Sivaprakash Ramalingam*, Anand R anganathan* and Shailja Singh*. “CRISPR/Cas9 mediated functional characterization of erythrocyte LC3-interacting region (LIR)-anchoring protein to develop host-targeted irresistible antimalarial”. Under Revision in Communications Biology-Nature; December 2023. #Contributted equally
Viji Vijayan, Ibrar Ahmad Siddique, Sakshi Gupta, Evanka Madan, Navya Raj, Sarika Gupta. “Osteocalcin Alters Aggregation Pattern of Abeta42 to Form Complexes (AO) that Aid in Amyloid Reduction in Mouse Models of Alzheimer Disease.” Communicated to Current Research in Pharmacology and Drug Discovery; April, 2024
Sudhaker Dharavath, Priya Tomar, Vijayan Ramachandran, Gargi Bhrigu, Faraz Mohd Khan, Evanka Madan, Rohini Muthuswami, Samudrala Gourinath “Inhibitors of Serine Acetyltransferase Induce Lethality in Entamoeba histolytica and Leishmnia donovani”. Communicated to European Journal of Medicinal Chemistry; June, 2024 (Manuscript Number: EJMECH-D-24-01720)
Harsh Pawar, Evanka Madan, Roni Nitzan Koren, Peter, J. Myler, Rentala Madhubala, Stephen M. Beverley and Dan Zilberstein. “A unique target of rapamycin kinase with a PDZ domain regulates the arginine sensing pathway in Leishmania”. Communicated to EMBO reports, February, 2024
A chapter entitled ‘Brain Tumors and Inflammation’ in a book on “Inflammation: the Common Link in Brain Pathologies” Khushboo Irshad, EvankaMadan, Kunzang Chosdol. Published in Springer; Aug, 2016, pp 253-280
A chapter entitled “Nuclear Factors Linking Cancer and Inflammation” in a book on “Nuclear Signaling Pathways and Targeting Transcription in Cancer” Kunzang Chosdol, Mohita Bhagat, Bhawana Dikshit, Evanka Madan, Parthaprasad Chattopadhyay, Subrata Sinha. Published in Cancer Drug Discovery and Development, 2014, pp 121-154
Evanka Madan, Madhu Puri, Zilberstein Dan, Rentala Madhubala “Molecular characterization of arginine sensing response in unravelling host-athogen interactions in Leishmania”. Abstract submitted to ICGEB Workshop: Molecular Biology of Leishmania, Italy, 2018. Published in The FEBS Journal, 2018 Page-16
Evanka Chopra, Vijay Pal Singh, Anurag Agrawal “Cardiovascular Disease in Metabolic Syndrome associated with metabolic induction of hypoxic response”. Abstract submitted to 16th World Cardiology Congress Conference, 2016. Published in J Clin Exp Cardiolog 2016, 7:12(Suppl) Page-33 ISSN:2155-9880
Evanka Madan Chopra, Vijay Pal Singh, Anurag Agrawal “Cardiovascular Disease in Metabolic Syndrome associated with metabolic induction of hypoxic response”. Abstract submitted to 12th International Conference of The Asian Clinical Oncology Society (ACOS), 2016. Published in Journal of Carcinogenesis, Vol 15, April, 2016
Eli Grunblatt, Evanka Madan, Sweta Roy, Sumanta Goswami. “Investigating the role of the anti-apoptotic protein ARC in breast cancer cell DNA repair”. Abstract submitted to AACR Annual Meeting. Published in Cancer Research; October, 2014
Chitrangda Srivastava, Khushboo Irshad, Evanka Madan, Srinivas H, Yakhlesh Gupta, Nargis Malik, Parthaprasad Chattopadhyay, Chitra Sarkar, Deepak Kumar Gupta, Subrata Sinha, Kunzang Chosdol. “FAT1 modulates the expression of molecular regulators of hypoxia and stemness in glioma” Abstract submitted toConference of The Asian Clinical Oncology Society (IACR), 2016. Published in Journal of Carcinogenesis, Vol 15, April, 2016
Evanka Madan, Bhawana Dikshit, Nupur Aggarwal, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol. “Expression of FAT1 and its influence on SWH (Salvador Warts Hippo) pathway in human glioma cell lines ”. Abstract submitted to 31st Annual Convention of the Indian Association for Cancer Research (IACR), 2012. Published in Journal of Cancer Research and Therapeutics, Vol 8, Supplement 1, January, 2012
Presentations/ Conferences & Symposiums Attended
Anchored many conferences entitled “30th National Congress of Parasitology and Global Summit on Malaria Elimination” and “ADVANCED CELL SORTING USING BECKMAN NEXT GENERATION CELL SORTER CYTOFLEX SRT” at JNU
Bagged best Young Researcher Award in 4th Science Conclave cum NBRCOM, SYBS, 2023, Alwar, India
Poster Presentation in “Research Opportunities in Germany & Recent advances in Biological Sciences”, JNU, New Delhi, 2023 and won best poster prize with a cash prize
Oral Presentation in ICID 2020:22th International Conference on Infectious Disease, Sydney, Australia and won best presentation award
Poster Presentation in 30th National Congress of Parasitology and Global Summit on Malaria Elimination, JNU, New Delhi, 2019 and won best poster prize
Oral & Poster Presentation in ICGEB Workshop: “Molecular Biology of Leishmania” 2018”, Treiste, Italy.
Poster Presentation in “IEC-VL Conference-2018”, Jamia Hamdard, New Delhi and won travel award
Oral Presentation in 16th Annual Scientific event “BIOSPARKS-2018”, JNU, New Delhi and won first prize
Oral Presentation on “Cardiovascular Disease in Metabolic Syndrome associated with metabolic induction of hypoxic response” in World Cardiology Congress Conference-2016, Dubai, UAE and bagged appreciation for it.
Symposium on “Metabolic Determinants of Stem Cell Pluripotency and Cell Fate Commitments” 2013, New York Academy of Sciences, New York, USA
Poster Presentation at Stony Brook University on “Investigating the Role of an Anti-Apoptotic Protein in Breast Cancer CellDNA Repair” 2013, New York, USA
Poster Presentation on “Expression of FAT1 and its influence on HIF1α axis in human glioma cell lines” in Inaugural Croucher Summer Course in Cancer Biology, 2013, University of Hong Kong, Hong Kong
Poster Presentation on “Expression of FAT1 and its influence on HIF1α axis in human glioma cell lines” in SYSCON -2013. Interfacing Basic and Translational Research, INSA, New Delhi, India and won Best Poster Award and the cash price
Won best Paper presentation award on “Expression of FAT1 and its influence on HIF1α axis in human glioma cell lines” in Symposium on “Frontiers in Neuroscience Research”, 2013, AIIMS-NBRC, New Delhi, India
Poster Presentation at the 31st Annual Convention of the Indian Association for Cancer Research (IACR), on “Expression of FAT1 and its influence on SWH (Salvador Warts Hippo) pathway in human glioma cell lines” 2012, ACTREC, Mumbai
Selected for the workshop on “Cancer Informatics – Analysis and Informatics of Microarray Data”, 2012, NCCS, Pune and Bioinformatics Centre, University of Pune, India
Ranbaxy Science Foundation Round Table Conference on "Targeted Therapy in the Malignancy: Where the future is?" 2011, AIIMS, New Delhi, India
Symposium on “Molecular Medicine” 2008, PGIMER, Chandigarh and won the 1st prize in debate
National Symposium on “Animal Remodeling: From Laboratory to Clinic” (INSA Sponsored) 2009, PGIMER, Chandigarh
Languages Spoken:
Education: BSc - Sri Venkateshwara College, Delhi University, New Delhi, India (2008) | MSc - PGIMER Chandigarh, India (2010) | Ph.D - AIIMS, New Delhi, India (2015)
IGIB (Institute of Genomics and Integrative Biology)
Research Associate
2015
- 2017
AIIMS
PhD Scholar
2010
- 2015
PGIMER, Chandigarh
M.Sc Fellow
2009
- 2010
Professional memberships
Training and Certifications
Differential Proteomics on High Resolution Mass Spectrometry
SCIEX, Centre of Excellence, Gurgaon, India
2018
- 2018
The Effect Of ARC on the DNA Repair Pathways of Breast Cancer Cells
Albert Einstein College of Medicine, New York, USA
2012
- 2013
Functional and Mutational Analysis of Myosin Heavy Chain in Cardiomyopathy
PGIMER, Chandigarh, India
2009
- 2010
Cloning of signal transduction genes (Rv0844c and Rv0490) from Mycobacteriun tuberculosis
Sri Venkateshwara College, Delhi University
2006
- 2007
Interests
Cardiometabolic Diseases, Tuberculosis, Leishmaniasis, Molecular Parasitology, Drug Discovery, and Cellular and Molecular Biology
Awards
Young Scientist Fellowship
ICMR-DHR (Grant money-15lac/year for 3 years) 2024
Bagged Best Young Researcher Award in 4th Science Conclave cum
NBRCOM, SYBS, Alwar, India 2023
Bagged Best Presentation Award for presenting work entitled “Molecular Characterization of Arginine Sensing Response in unraveling Host-pathogen Interactions in Leishmania
ICID Conference-2020, Sydney, Australia 2020
Certificate of Competence
Lab animals for Handling, Care at JNU 2020
Certificate of Appreciation
Session Chair in ICID-2020 2020
First prize for Oral presentation in 16th Annual scientific event “BIOSPARKS-2018”
JNU, New Delhi, India 2018
Bagged Travel Award from PLOS NTD for poster presentation at IEC-VL Conference-2018
Jamia Hamdard, N-Delhi 2018
CSIR-Scientist Pool Officer/Nehru, UGC D.S. Kothari
2018
Scientific talk on PhD thesis work at Third Biannual Meet of Delhi-NCR Basic Neuro-Oncology group
AIIMS, New Delhi 2016
Delivered a talk as a speaker in 16th World Cardiology Congress Conference
Dubai, UAE 2016
Best Poster Award with cash price for Poster Presentation on “Expression of FAT1 and its influence on HIF1α axis in human glioma cell lines”
SYSCON-2013...Interfacing Basic and Translational Research, INSA, New Delhi, India 2013
Best Paper Presentation Award for Presentation on “Expression of FAT1 and its influence on HIF1α axis in human glioma cell lines” in Symposium on “Frontiers in Neuroscience Research”
AIIMS, New Delhi, India 2013
Third position in B. Sc (H) (Biological Sciences)
Delhi University 2008
Book Appointment
Dr. Evanka Madan
Consultant and Assistant Professor
Department of Biotechnology and Research
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Video 1400 Rs.
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