Greetings from the Multi-Omics Core Facility, Department of Biotechnology and Research at Sir Ganga Ram Hospital in New Delhi.
About Us
We at Sir Ganga Ram Hospital's Multi-Omics Core Facility are committed to using futuristic and modern proteomics and metabolomics technologies to further biomedical research. Our innovative facility provides a full range of services and knowledge intended to enhance and support diagnosis and research in these fast-paced domains.
Our Services
Proteomics
Utilise our sophisticated proteomics skills to unravel the intricacies of protein expression, function, and interactions:
- Quantitative Proteomics: To find biomarkers and comprehend disease causes, quantitative proteomics measures protein abundance accurately.
- Protein Identification: For in-depth protein characterization and annotation, high-resolution mass spectrometry is used.
- Protein-Protein Interactions: Use advanced methods and instruments to examine interactions and pathways.
- Custom Proteomics Solutions: Methods designed to satisfy particular project objectives and research requirements.
Metabolomics
Use our extensive metabolomics services to investigate the metabolic landscape:
- Global Metabolite Profiling: In-depth examination of metabolites to comprehend illness conditions and metabolic alterations.
- Targeted Metabolomics: Analysing particular metabolic pathways or chemicals of interest is known as targeted metabolomics.
- Flux Analysis: Analysing metabolic fluxes to uncover dynamic shifts in metabolic pathways is known as flux analysis.
- Custom Metabolomics Projects: Tailored assistance for certain research goals and difficulties.
Lipidomics
Use our extensive lipidomics services to delve into the complex realm of lipids:
- Global Lipid Profiling: Comprehensive examination of lipid species to comprehend metabolic alterations and illness conditions linked to lipids.
- Targeted lipidomics: It is the study of particular lipid classes or pathways of interest in order to determine how they relate to health and illness.
- Lipid Metabolism and Dynamics: To identify the dynamic shifts in lipid metabolism, lipid fluxes and metabolic pathways are studied.
- Custom Lipidomics Projects: Support specifically designed to meet the particular requirements and difficulties of lipidomic research.
Bioinformatics Analysis
- Proteome Discoverer: We provide expert services in protein identification, quantification, and analysis using Proteome Discoverer to unlock valuable insights from your proteomics data.
- Compound Discoverer: Our services offer advanced metabolomics and small molecule analysis with Compound Discoverer, enabling precise identification and quantification of metabolites in complex samples.
- Lipid Search: We specialize in lipidomic analysis using LipidSearch, providing in-depth profiling and quantification of lipid species for your research and clinical studies.
Diagnostics
A futuristic Triple Quadrupole (Triple Quad) LC-MS/MS system in our facility allows us to carry out a variety of sophisticated diagnostic procedures. High sensitivity, selectivity, and accuracy in identifying and measuring trace amounts of chemicals are made possible by this potent equipment. To ensure accurate diagnoses for a range of research and clinical applications, we can do complicated studies, such as quantitative and qualitative examination of pharmaceuticals, biomarkers, environmental pollutants, and more. For a wide range of applications, our proficiency with Triple Quad-based diagnostics ensures dependable outcomes.
Our Technology
Our facility has the latest equipment and technology, such as:
- Thermo Fisher Fortis Plus System with Vanquish HPLC: A high-performance liquid chromatography system for accurate separation and analysis of intricate biological materials is the Thermo Fisher Fortis Plus System with Vanquish HPLC.
- Orbitrap Exploris 240 with Nano LC: For proteome and metabolomic investigations, the Orbitrap Exploris 240 with Nano LC is a high-resolution mass spectrometry instrument that provides remarkable sensitivity and precision.
- High-Resolution Mass Spectrometry: For in-depth metabolomic and proteome analysis.
- Liquid Chromatography-Mass Spectrometry (LC-MS): Sophisticated methods for biomolecule separation and analysis.
- Bioinformatics Platform: Proteomics and metabolomics data analysis using an advanced bioinformatics platform.
Our Team
Introducing our team of professionals, each with extensive backgrounds in bioinformatics, metabolomics, and proteomics. Our devoted scientists and support team are committed to providing individualized care and excellent results.
Prof. (Dr.) N K Ganguly, (Former DG ICMR) Chairman, Department of Biotechnology & Research
Dr. Rashmi Rana, Senior Scientist & In-charge
Dr. M H Yashavarddhan, Scientist
Dr. Sunny, Bioinformatician
Ms. Pooja Sharma, Mass Spec Analyst
Publications & Resources
- Sharma S, Shamjetsabam ND, Chauhan K, Yashavarddhan MH, Gautam P, Prakash P, Choudhary P, Chhabra SS, Acharya R, Kalra SK, Gupta A. Quantitative tissue analysis reveals AK2, COL1A1, and PLG protein signatures: targeted therapeutics for meningioma. International Journal of Surgery. 2024 Dec 1;110(12):7434-46.
- Rana R, Chauhan K, Gautam P, Kulkarni M, Banarjee R, Chugh P, Chhabra SS, Acharya R, Kalra SK, Gupta A, Jain S. Plasma-derived extracellular vesicles reveal galectin-3 binding protein as potential biomarker for early detection of glioma. Frontiers in Oncology. 2021 Nov 26;11:778754.
Training & Workshops
To assist researchers in becoming proficient in proteomics and metabolomics methods, we provide workshops and training sessions. Keep an eye out for forthcoming occasions and chances to improve your abilities.
Upcoming Events
Learn More
News & Updates
Keep up with our facility's most recent announcements, developments, and news.
Read Our Blog
We appreciate your visit to Sir Ganga Ram Hospital's Multi-Omics Core Facility. We are eager to support your research and assist you in reaching your scientific objectives.
Collaborate With Us
To promote scientific innovation and discovery, we invite partnerships with researchers, physicians, and organisations. Our team is available to assist you whether you want to use our services, collaborate on projects, or pursue new lines of inquiry.
Sample Requisition Form (Download)
Price list (Download)
Contact Us | Schedule Your Bookings
Email: support.mocf@sgrh.com
Phone: +91-11-4225-1250
Location: Multi-Omics Core Facility, Department of Biotechnology and Research, Room No1250, Casualty Block, Second Foor, Sir Ganga Ram Hospital, Old Rajinder Nagar, New Delhi, India. Pin- 110060
